Patent · US Active

Expansion of alloantigen-reactive regulatory T cells

US9801911B2 · kind B2 · utility

2Cited by

11References

9Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Qizhi Tang · Oakland, US
Jeffrey A. Bluestone · San Francisco, US

Key dates

Filing date	Mar 1, 2013
Grant date	Oct 31, 2017
Priority date	—
Expiry date	Oct 9, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2502/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates generally to the manufacture of regulatory T cells (Tregs) for use in immunotherapy. In particular, the present disclosure relates to robust approaches for the expansion of alloantigen-reactive Tregs ex vivo. Alloantigen-reactive Tregs produced in this way are suitable for the induction and/or maintenance of immunologic tolerance in recipients of allogeneic transplants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.