Immune tolerance inducer
US9801929B2 · kind B2 · utility
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2References
5Claims
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Key dates
| Filing date | Jul 13, 2012 |
| Grant date | Oct 31, 2017 |
| Priority date | — |
| Expiry date | Jul 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An object of the present invention is to provide a drug and a method for effectively inducing donor-specific immune tolerance in a recipient in transplantation therapy. A complex of an siRNA for a costimulatory factor and schizophyllan is delivered to a Dectin-1 expressing cell which specifically recognizes schizophyllan to regulate the function of the Dectin-1 expressing cell, and therefore can induce immunosuppression effect as well as induce immune tolerance effectively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.