Patent · US Active

Adenovirus derived helper virus for enhancing recombinant parvovirus production

US9803219B2 · kind B2 · utility

1Cited by

3References

9Claims

0Family size

Assignee

Deutsches Krebsforschungszentrum · DE

Inventors

Nazim El-Andaloussi · Heidelberg, DE
Antonio Marchini · Heidelberg, DE
Jean Rommelaere · Heidelberg, DE
Barbara Leuchs · Heidelberg, DE
Max Endele · Wilhelmsfeld, DE

Key dates

Filing date	Sep 26, 2012
Grant date	Oct 31, 2017
Priority date	—
Expiry date	Sep 26, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/14352
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described is an adenovirus derived helper virus which may comprise the adenoviral DNA sequences for E2a, S4 (orf6), the VA1 RNA gene, and the parvovirus VP capsid gene unit. Also described is a method of efficiently preparing a recombinant parvovirus (particle) which is based on the use of various adenoviral derived helper viruses/vectors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.