Recognition-release nanoporous substrate comprising active agents, methods of their preparation and uses
US9803233B2 · kind B2 · utility
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16Claims
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Assignee
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Key dates
| Filing date | Dec 5, 2013 |
| Grant date | Oct 31, 2017 |
| Priority date | — |
| Expiry date | Dec 5, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a porous substrate comprising at least one active agent entrapped within said pores of said substrate; wherein said pores are capped by at least one nucleic acid sequence; said agent is being released by a triggered reaction of said capping sequence with at least one analyte (biomarker) thereby allowing said capping to be cleaved from said pore. The invention further relates to methods of manufacturing said substrate, uses thereof for the controlled administration of active agents and diagnostic of conditions in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.