Patent · US Active

Silicon dioxide nanoparticles and the use thereof for vaccination

US9808521B2 · kind B2 · utility

2Cited by

2References

19Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Markus Weigandt · Mannheim, DE
Andrea Hanefeld · Darmstadt, DE
Armin Kuebelbeck · Bensheim, DE
Gregor Larbig · Gelnhausen, DE

Key dates

Filing date	Jun 30, 2016
Grant date	Nov 7, 2017
Priority date	—
Expiry date	Jun 30, 2036

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2982
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunization of a mammal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.