Isopropyl triazolo pyridine compounds

US9809592B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Chafiq Hamdouchi · Carmel, US
• Pranab Maiti · Narayanpur, IN
• Anne Reifel Miller · Indianapolis, US

Key dates

• Filing date: Jan 6, 2015
• Grant date: Nov 7, 2017
• Expiry date: Jan 6, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a compound of the Formula (I) below: Wherein R1 is selected from the group consisting of H, CH3, CN, CH2CN, C(CH3)2CN, and F; R2 is selected from the group consisting of H, O(C1-C3alkyl)R5, CH2CN, and CN; R3 is selected from the group consisting of H, OCH3, CN, C(CH3)2CN, and CH2CN; R4 is selected from the group consisting of H and CH3; R5 is selected from the group consisting of H, CN, C(CH3)2CN, OCH3, S(O)2CH3, and C(CH3)2OH; provided that at least one selected from the group consisting of R1, R2, R3 and R4 is H; or a pharmaceutically acceptable salt thereof, methods of treating diabetes using the compound and a process for preparing the compound.