Broad spectrum beta-lactamase inhibitors
US9809605B1 · kind B1 · utility
4Cited by
68References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 21, 2017 |
| Grant date | Nov 7, 2017 |
| Priority date | — |
| Expiry date | Jul 21, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D501/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.