Silylation of aromatic heterocycles by earth abundant transition-metal-free catalysts
US9809607B2 · kind B2 · utility
10Cited by
1References
37Claims
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Key dates
| Filing date | Aug 5, 2015 |
| Grant date | Nov 7, 2017 |
| Priority date | — |
| Expiry date | Aug 5, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/0832
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention describes chemical systems and methods for silylating aromatic organic substrates, said system or method comprising or consisting essentially of a mixture of (a) at least one organosilane and (b) at least one strong base, the definition of strong base now also including KOH, said system being preferably, but not necessarily substantially free of a transition-metal compound, and said methods comprising contacting a quantity of the organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the aromatic substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.