Transforming growth factor beta receptor II fusion polypeptides
US9809637B2 · kind B2 · utility
18Cited by
23References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 16, 2016 |
| Grant date | Nov 7, 2017 |
| Priority date | — |
| Expiry date | Feb 16, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.