Pathways to adipate semialdehyde and other organic products
US9809833B2 · kind B2 · utility
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Key dates
| Filing date | Sep 20, 2013 |
| Grant date | Nov 7, 2017 |
| Priority date | — |
| Expiry date | Oct 30, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y402/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Recombinant microorganisms comprising at least one exogenous nucleic acid sequence and capable of producing adipate semialdehyde are provided. Adipate semialdehyde may be produced in a synthesis pathway utilizing a single thiolase reaction. Adipate semialdehyde may also be produced from intermediates consisting of alpha, omega difunctional aliphatic organic molecules. Methods of using recombinant microorganisms to produce 6-aminocaproic acid, adipic acid, hexamethylenediamine and 1.6-hexanediol are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.