Nanogap electronic detector for measuring properties of a biomolecule stretched in a nanochannel, and method thereof
US9810680B2 · kind B2 · utility
3Cited by
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42Claims
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Key dates
| Filing date | Apr 16, 2010 |
| Grant date | Nov 7, 2017 |
| Priority date | — |
| Expiry date | Jul 18, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods and apparatus for measuring a property of an sample, the apparatus can manipulate, detect, and analyze the sample composed of single molecules, single small particles or single small samples of matter by drawing the sample into a nanofluidic channel and stretching the sample within the channel, passing the stretched sample through a gap having a width of less than or equal to 20 nm of a nanogap detector positioned inside or adjacent to the nanofluidic channel and measuring an output from the nanogap detector representative of the property of the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.