Use of live cell inteferometry with reflective floor of observation chamber to determine changes in mass of mammalian cells
US9810683B2 · kind B2 · utility
6Cited by
8References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 25, 2013 |
| Grant date | Nov 7, 2017 |
| Priority date | — |
| Expiry date | Oct 24, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B21/32
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides optical systems and methods for determining a characteristic of a cell, such as cell type, cellular response to a biochemical event, biological state and the like. The methods typically involve using interferometry to observe membrane properties in a cell and then use this information to determine one or more characteristics of a cell. The methods of the invention are useful for applications such as drug screening as well as diagnostic techniques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.