Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols
US9815809B2 · kind B2 · utility
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Key dates
| Filing date | Jul 3, 2014 |
| Grant date | Nov 14, 2017 |
| Priority date | — |
| Expiry date | Jul 3, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/09
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.