Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors
US9815817B2 · kind B2 · utility
24Cited by
2References
48Claims
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Key dates
| Filing date | Sep 18, 2015 |
| Grant date | Nov 14, 2017 |
| Priority date | — |
| Expiry date | Sep 18, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula:where A, B, W1, W2, W3, and R1-R6 are described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.