Method for producing 4-borono-L-phenylalanine having 18F atom introduced thereinto, and precursor of 4-borono-L-phenylalanine having 18F atom introduced thereinto
US9815855B2 · kind B2 · utility
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Key dates
| Filing date | Jan 28, 2015 |
| Grant date | Nov 14, 2017 |
| Priority date | — |
| Expiry date | Jan 28, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
18F-labeled 4-boronophenylalanine (BPA) can be produced by preparing and further processing a precursor of 18F-labeled BPA represented by the following formula:in which R1 represents a bromo group, an iodo group, a fluoro group, a diazaborinane derivative, BX3− or BX3−M+ (wherein X represents a halogen atom; and M+ represents a monovalent monoatomic cation, a polyatomic cation or a complex cation).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.