Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof
US9815872B2 · kind B2 · utility
2Cited by
8References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 18, 2014 |
| Grant date | Nov 14, 2017 |
| Priority date | — |
| Expiry date | Jun 18, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides delta toxin and phenol-soluble modulin peptides as well as mutants, fragments, variants or derivatives thereof. The disclosure further provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal proteins, e.g., DT, PSM, alpha hemolysin, leukocidin, superantigen, or any fragments, variants, derivatives, or mutants thereof fused together as a single polypeptide in any order.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.