Monoclonal antibody which is specifically bound to TM4SF5 protein and use thereof
US9815900B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 3, 2015 |
| Grant date | Nov 14, 2017 |
| Priority date | — |
| Expiry date | Jun 4, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4703
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a novel monoclonal antibody which is specifically bound to a transmembrane 4 L six family member 5 (TM4SF5) protein. More particularly, the present invention relates to a monoclonal antibody which is specifically bound to a human TM4SF5 protein, to polynucleotides coding for the monoclonal antibody, to an expression vector comprising the nucleotides, to a transformant with the vector introduced thereto, to a method for preparing the monoclonal antibody, to a composition comprising the monoclonal antibody, to a method for treating liver fibrosis using the monoclonal antibody, to a method for treating cancer using the monoclonal antibody, to a method for inhibiting metastasis of cancer, to a method for diagnosing cancer using the monoclonal antibody and to a cancer diagnosis kit comprising the monoclonal antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.