Biomarker specific amphiphilic nanoparticles
US9815945B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Nov 12, 2014 |
| Grant date | Nov 14, 2017 |
| Priority date | — |
| Expiry date | Nov 12, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G83/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an amphiphilic nanoparticle specific to a biomarker, and more particularly, provides an amphiphilic nanoparticle which may be used as a diagnosis or treatment-type drug or gene carrier by selectively recognizing a proteolytic enzyme specifically expressed in a cellular membrane of a specific cell, and then being bound to the proteolytic enzyme to efficiently achieve the intracellular uptake and selective cleavage. The amphiphilic nanoparticle of the present invention may be used in the diagnosis or therapy of a disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.