Patent · US Active

CHO integration sites and uses thereof

US9816110B2 · kind B2 · utility

7Cited by
4References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 21, 2015
Grant dateNov 14, 2017
Priority date
Expiry dateOct 21, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/85
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.