Devices and methods for assessing motor point electromyogram as a biomarker
US9820671B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 16, 2008 |
| Grant date | Nov 21, 2017 |
| Priority date | — |
| Expiry date | Oct 6, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/3601
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Described herein are methods of detecting the presence or progression of neuromuscular disorders (including ALS) based at least in part on diaphragm EMG signals taken at different points in time from the same implanted electrode(s). Signals may be used to diagnose or to monitor progression of a disorder or to track a treatment. Thus, diaphragm EMG signal may be used as a marker (e.g., a “biomarker”) for the detection or progression of a neurological disorder such as ALS. The characteristics or parameters of diaphragm EMG signals may be used to create an activity index, which may be output or compared and further analyzed. These signals may also be analyzed to show a difference between the left and right sides of the diaphragm.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.