Methods of treating autoimmunity

US9820957B2 · kind B2 · utility

Assignee

• The Regents of the University of Colorado, a Body Corporate · US

Inventors

• Steve Orndorff · Broomfield, US
• Aaron Michels · Aurora, US
• Peter Gottlieb · Wheelock, US

Key dates

• Filing date: Mar 22, 2017
• Grant date: Nov 21, 2017
• Expiry date: Mar 22, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/042
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods of treating, ameliorating, or inhibiting the development of autoimmune diseases by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease. The binding may be modulated by the administration of D-α-methyldopa, or pharmaceutical compositions comprising therapeutically effective amounts of D-α-methyldopa.