Chimeric dengue virus E glycoproteins comprising mutant domain I and domain II hinge regions
US9821050B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Mar 15, 2013 |
| Grant date | Nov 21, 2017 |
| Priority date | — |
| Expiry date | Jun 21, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein domain I and domain II hinge region from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.