Heat-sensitive nanoparticle system

US9821060B2 · kind B2 · utility

Assignee

• FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA · IT

Inventors

• Andreas Riedinger · Schwäbisch Gmünd, DE
• Teresa Pellegrino · Lecce, IT
• Pablo Guardia Giros · Barcelona, ES
• Alberto Curcio · Torre Annunziata, IT
• Roberto Cingolani · Genova, IT
• Liberato Manna · Palo del Colle, IT

Key dates

• Filing date: Jan 28, 2014
• Grant date: Nov 21, 2017
• Expiry date: Jul 30, 2034

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2982
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A heat-sensitive system comprising at least one nanoparticle bound covalently to at least one thermolabile molecule comprising an azo —N═N— functional group —N═N— in turn bound covalently to at least one active molecule selected from a fluorophore molecule and a drug is disclosed. The system converts an electromagnetic radiation into thermal energy exposed to an alternating magnetic field. Uses of the system are also disclosed.