Lipopeptides for delivery of nucleic acids
US9821067B2 · kind B2 · utility
6Cited by
2References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 16, 2015 |
| Grant date | Nov 21, 2017 |
| Priority date | — |
| Expiry date | Nov 16, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Lipopeptide compounds having a central peptide HHHHHKHHHKKKHKHKKK (SEQ ID NO:15) and a lipophilic group attached to each terminus of the peptide, and salts thereof. The lipopeptides are useful for forming pharmaceutical compositions for delivery of nucleic acid agents, such as siRNA and mdRNA agents, as well as in methods for treating the signs and symptoms of disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.