GAK modulators as antivirals

US9822127B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Steven De Jonghe · Brussels, BE
• Piet Herdewyn · Heverlee, BE
• Elena Bekerman · Castro Valley, US
• Shirit Einav · Stanford, US
• Gregory Neveu · Palo Alto, US

Key dates

• Filing date: Jul 23, 2015
• Grant date: Nov 21, 2017
• Expiry date: Jul 23, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to the use of a class of novel isothiazolo[4,3-b]pyridine derivatives as well as to pharmaceutical compositions comprising one or more of said isothiazolo[4,3-b]pyridine derivatives and one or more pharmaceutically acceptable excipients as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as viral diseases.