Means and methods for influencing the stability of antibody producing cells
US9822339B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Aug 26, 2015 |
| Grant date | Nov 21, 2017 |
| Priority date | — |
| Expiry date | Jan 18, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.