Compositions and methods using capsids resistant to hydrolases
US9822361B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jun 5, 2014 |
| Grant date | Nov 21, 2017 |
| Priority date | — |
| Expiry date | Jun 5, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/18142
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNAs and shRNAs, miRNAs, messenger RNAs, small peptides and bioactive molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.