Patent · US Active

Compositions and methods for the modulation of gene expression in plants

US9822376B2 · kind B2 · utility

0Cited by

30References

8Claims

0Family size

Assignee

UNIVERSITY OF SOUTH CAROLINA · US

Inventors

Viki Bowman Vance · Columbia, US
Lewis H. Bowman · Columbia, US
Allison Mallory · Paris, FR

Key dates

Filing date	Oct 27, 2011
Grant date	Nov 21, 2017
Priority date	—
Expiry date	Mar 11, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/8218
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Compositions and methods for modulating nucleotide sequence expression, particularly for modulating gene expression in plants, are provided. The compositions comprise precursor RNA constructs for the expression of an RNA precursor. The precursor RNA construct comprises a promoter that is expressed in a plant cell driving the expression of a precursor RNA having a microRNA. The miRNA is complementary or partially complementary to a portion of a target gene or nucleotide sequence and function to modulate expression of the target sequence or gene. In this manner, the RNA precursor construct can be designed to modulate expression of any nucleotide sequence of interest, either an endogenous plant gene or alternatively a transgene. Transformed plants, tissues, cells and seeds are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.