Patent · US Active

Renal neuromodulation methods and devices for treatment of polycystic kidney disease

US9827042B2 · kind B2 · utility

0Cited by
108References
19Claims
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Inventor

Key dates

Filing dateSep 11, 2015
Grant dateNov 28, 2017
Priority date
Expiry dateSep 11, 2035

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61N1/36017
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Methods for treating polycystic kidney disease with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. One or more measurable physiological parameter corresponding to the polycystic kidney disease can thereby be reduced. Moreover, central sympathetic drive in the patient can be reduced in a manner that treats the patient for the polycystic kidney disease. Renal sympathetic nerve activity can be modulated along the afferent and/or efferent pathway. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a neuromodulation assembly, e.g., a neuromodulation assembly configured to cryotherapeutically cool the renal nerve or to deliver an energy field to the renal nerve.

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