Enzyme interacting agents

US9828351B2 · kind B2 · utility

Assignees

• MONASH UNIVERSITY · AU
• UNIVERSITY OF SOUTH AUSTRALIA · AU
• Central Adelaide Local Health Network Incorporated · AU

Inventors

• Bernard Luke Flynn · Melbourne, AU
• Luigi Aurelio · Melbourne, AU
• Carmen Vittoria Scullino · Melbourne, AU
• Bing Wang · San Jose, US
• Stuart Pitson · Pimba, AU
• Melissa Rose Pitman · Blackwood, AU

Key dates

• Filing date: Jun 26, 2015
• Grant date: Nov 28, 2017
• Expiry date: Jun 26, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D419/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure relates generally, but not exclusively, to compounds and their use as enzyme interacting agents, in particular, agents which interact with one or more enzymes in the sphingolipid biosynthesis pathway. The disclosure further relates to the use of such compounds as research tools, use in therapy, to compositions and agents comprising said compounds, and to methods of treatment using said compounds.