Vancomycin derivative, and preparation method and application thereof
US9828413B2 · kind B2 · utility
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1References
12Claims
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Assignee
Inventor
Key dates
| Filing date | Apr 22, 2014 |
| Grant date | Nov 28, 2017 |
| Priority date | — |
| Expiry date | Apr 22, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a vancomycin derivative, and a preparation method and an application thereof. The vancomycin derivative of the present invention is obtained by introducing a glycerate moiety between a vancomycin derivative and a liposoluble modification group and has reduced liposolubility and improved water solubility, thereby reducing a side effect in the cardiovascular aspect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.