Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
US9828614B1 · kind B1 · utility
10Cited by
7References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 20, 2017 |
| Grant date | Nov 28, 2017 |
| Priority date | — |
| Expiry date | Sep 20, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.