Chromosome copy number gain as a biomarker of urothelial carcinoma lethality
US9828643B2 · kind B2 · utility
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Key dates
| Filing date | May 18, 2012 |
| Grant date | Nov 28, 2017 |
| Priority date | — |
| Expiry date | May 27, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/112
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Diagnostic assays for medically classifying cancer patients are provided. The method comprises assessing a tissue sample of the patient for the presence of a copy number gain of chromosome regions 1q23.3 and/or 1q21.2. Copy number gain of chromosome regions 1q23.3 and/or 1q21.2 is indicative of a less favorable prognosis as compared to the prognosis if there was no copy number gain in the same regions.
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