External cavity laser biosensor arrangements
US9829435B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 29, 2012 |
| Grant date | Nov 28, 2017 |
| Priority date | — |
| Expiry date | Nov 26, 2035 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01S5/142
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A label-free biosensor detection arrangement incorporating an external cavity laser (ECL) includes a tunable lasing element (e.g. an antireflection coated laser diode or semiconductor optical amplifier) and a narrow bandwidth resonant reflectance filter as the wavelength-selective element for the tunable lasing element. A sample is deposited on the surface of the resonant reflectance filter containing a biological material. The wavelength emitted by the external cavity laser is continuously tunable by binding interactions between the biological material and the resonant reflectance filter or adsorption of the biological material present in the sample on resonant reflectance filter. The narrow bandwidth resonance reflectance filter can take the form of photonic crystal (PC), a Bragg stack, or a Brag fiber reflection filter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.