Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
US9834528B2 · kind B2 · utility
4Cited by
2References
44Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 2016 |
| Grant date | Dec 5, 2017 |
| Priority date | — |
| Expiry date | Aug 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides α-amino esters of a hydroxypropylthiazolidine carboxamide derivative, (2S)-3-([1,1′-biphenyl]-4-ylsulfonyl)-N-[(1S)-3-hydroxy-1-phenylpropyl]-1,3-thiazolidine-2-carboxamide, as well as salts and crystal polymorph s thereof, that can be used to inhibit prostaglandin F receptor. The invention further encompasses methods of treating disorders such as pre-term labor at the early gestational stage by the administration of these substances to a patient in need of treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.