Process for the preparation of gemcitabine-[phenyl(benzoxy-L-alaninyl)] phosphate

US9834577B2 · kind B2 · utility

Assignee

• LAURUS LABS LIMITED · IN

Inventors

• Venkata Lakshmi Narasimha Rao Dammalapati · Hyderabad, IN
• Mani Bushan Kotala · Mandal, IN
• Shankar Madhavaram · Hyderabad, IN

Key dates

• Filing date: Jul 22, 2015
• Grant date: Dec 5, 2017
• Expiry date: Jul 22, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H1/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides a process for the preparation of gemcitabine-[phenyl(benzoxy-L-alaninyl)] phosphate of Formula I in high yield and purity.