Rapid small volume detection of blood ammonia

US9835613B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Thomas Richard Veltman · Towson, US
• Chun-Jung Tsai · Cupertino, US
• Matthew W. Kanan · Palo Alto, US
• Gilbert Chu · Palo Alto, US

Key dates

• Filing date: Oct 14, 2016
• Grant date: Dec 5, 2017
• Expiry date: Oct 14, 2036

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/20
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for measuring ammonia in a blood sample may involve positioning the blood sample in proximity with an ammonia gas sensor, generating a current with the ammonia gas sensor in response to ammonia gas released from the blood sample, and measuring the current generated by the ammonia gas sensor, using a current measurement member coupled with the ammonia gas sensor. A device for measuring an ammonia level in a blood sample may include a blood sample containment member, an ammonia gas sensor coupled with the blood sample containment member, and a current measurement member coupled with the ammonia gas sensor. The method and device may be used to measure an ammonia level in a blood sample as small as one drop of blood, or approximately 0.05 mL of blood.