Measurement of cell growth and drug susceptibility by resonant mass measurement
US9835614B2 · kind B2 · utility
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23Claims
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Key dates
| Filing date | Sep 8, 2014 |
| Grant date | Dec 5, 2017 |
| Priority date | — |
| Expiry date | Sep 8, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
System and Method for measuring the growth of a bacterial culture and its response to one or more antimicrobials using measurement of mass of individual microbes. Methods include periodic sampling, determining change in mass and concentration, and comparing growth rates of cultures in nutrient broth vs. mixtures containing various antibiotic mixtures. A number of antimicrobials can be compared in one measurement by multiplexing or using multiple sensors to measure in parallel. Growth and antibiotic efficacy can be assessed at low concentrations at the onset of growth, typically within 1 to 2 hours.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.