Patent · US Active

Double-stranded polyethylene glycol modified growth hormone, preparation method and application thereof

US9840546B2 · kind B2 · utility

0Cited by

5References

64Claims

0Family size

Assignee

Biosteed Gene Expression Tech. Co., Ltd. · CN

Inventors

Weidong Zhou · Warren, US
Xiaojin LIAO · Fujian, CN
Li Jing Sun · Hexi District, CN
LINZHONG ZHANG · Fujian, CN
Qingsong Lu · Longbeilingcun, CN
Shiye Shen · Fujian, CN
Lishan YANG · Fujian, CN
Defang Zhang · Fujian, CN
Huihuang Lin · Fujian, CN
Ping Zhang · Guelph, CA

Key dates

Filing date	Apr 3, 2008
Grant date	Dec 12, 2017
Priority date	—
Expiry date	Aug 20, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The growth hormone with high biological activity modified by the double-stranded polyethylene glycol at a single site and the preparation method thereof are provided. The PEGylated growth hormone has a higher biological activity and a longer half-life than the unmodified growth hormone. The composition comprising the PEGylated growth hormone is useful in the treatment of the growth or development disorder such as growth hormone deficiency, Turner syndrome etc.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.