Monoclonal antibody against human midkine
US9840552B2 · kind B2 · utility
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Key dates
| Filing date | Jul 30, 2013 |
| Grant date | Dec 12, 2017 |
| Priority date | — |
| Expiry date | Jul 30, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A monoclonal antibody, which recognizes at least two amino acids among amino acids located at position 69, position 79, position 81 and position 102 of human midkine, has been found to have excellent reactivity with and excellent neutralizing activity against human midkine. Moreover, the activity of suppressing the proliferation of tumor has been observed in the antibody having excellent neutralizing activity. The use of the antibody of the present invention makes it possible to treat cancer effectively and to detect or purify midkine efficiently.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.