Patent · US Active

Variant AAV and compositions, methods and uses for gene transfer to cells, organs and tissues

US9840719B2 · kind B2 · utility

16Cited by
3References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 22, 2014
Grant dateDec 12, 2017
Priority date
Expiry dateFeb 1, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2830/008
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer methods and uses. In particular, AAV-Rh74 and related AAV vectors target polynucleotides to cells, tissues or organs for expression (transcription) of genes encoding therapeutic proteins and peptides, and polynucleotides that function as or are transcribed into inhibitory nucleic acid sequences.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.