Immuno imaging agent for use with antibody-drug conjugate therapy

US9844607B2 · kind B2 · utility

Assignees

• Sanofi · FR
• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Jochen Kruip · Frankfurt am Main, DE
• Sanjiv S. Gambhir · Portola Valley, US
• Susanta Kumar Sarkar · Highlands Ranch, US
• Mathias Gebauer · Frankfurt, DE
• Christian Lange · Frankfurt am Main, DE
• Ingo Focken · Hofheim, DE
• Richard H. Kimura · Stanford, US
• Arutselvan Natarajan · Sunnyvale, US
• Ohad Ilovich · Even Yehuda, IL

Key dates

• Filing date: Feb 5, 2014
• Grant date: Dec 19, 2017
• Expiry date: Apr 9, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a companion diagnostic antibody-like binding protein based on the humanized monoclonal antibody, DS6, to be used as diagnostic tool for in vivo detection and quantification of the tumor-associated MUC1-sialoglycotope, CA6.