Patent · US Active

Class of near infrared optical probes for biological applications

US9845318B2 · kind B2 · utility

0Cited by

0References

13Claims

0Family size

Assignee

THE UNIVERSITY OF AKRON · US

Inventors

Yi Pang · Ames, US
Yongqian Xu · Nanjing, CN

Key dates

Filing date	Feb 3, 2015
Grant date	Dec 19, 2017
Priority date	—
Expiry date	Jan 30, 2036

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/84
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

2,5-Bis(benzoxazol-2′-yl)benzene-1,4-diol derivatives (Zinhbo derivatives) are used to detect zinc ions and have particular application in vivo and in vitro. Zinhbo derivatives upon excitation give a florescence response emission that can be used to determine the presence of zinc cation in solution. Zinhbo derivatives complexed with zinc cations upon excitation can produce a florescence response emission in the visible and near infrared range. Zinhbo derivatives complexed with zinc cations exhibit a large stoke shift between the excitation and emission wavelengths.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.