Therapeutic use of a growth factor, NsG33
US9845344B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Mar 30, 2005 |
| Grant date | Dec 19, 2017 |
| Priority date | — |
| Expiry date | Apr 5, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/027
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the field of therapeutic use of proteins, genes and cells. More specifically the invention relates to therapy based on the biological function of a secreted therapeutic protein, NsG33, in particular for the treatment of disorders of the nervous system. NsG33 is a nerve survival and growth factor with antiapoptotic effects on a cell line with neuronal potential and with neuroprotective and/or neurogenesis effects on a neural precursor cell line and on primary striatal cultures. The invention also relates to novel bioactive NsG33 polypeptide fragments and the corresponding encoding DNA sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.