SIRP polypeptide compositions and methods of use

US9845345B2 · kind B2 · utility

Assignee

• Ab Initio Biotherapeutics, Inc. · US

Inventors

• Aaron Michael Ring · New Haven, US
• Roy Louis Maute · San Francisco, US
• Andrew Kruse · Brookline, US
• Aashish Manglik · Menlo Park, US
• Kenneth Lin · Rancho Santa Margarita, US

Key dates

• Filing date: May 17, 2016
• Grant date: Dec 19, 2017
• Expiry date: May 17, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/50
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are SIRP-gamma, SIRP-beta or SIRP-beta2 decoy polypeptides for immunotherapy and/or treatment of cancer, anemia, transplant, asthma, allergy, auto-immune disease, and viral infection.