Prediction of therapeutic response in inflammatory conditions
US9845505B2 · kind B2 · utility
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Key dates
| Filing date | Jan 29, 2016 |
| Grant date | Dec 19, 2017 |
| Priority date | — |
| Expiry date | Jan 29, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B99/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Response to treatment of an inflammatory condition can be predicted based on characteristics of one or more markers from a subject. The markers can include expressions of nucleotide sequences identified herein and of combinations thereof. A response value can be calculated based on characteristics (e.g., expression levels) of one or more of the markers, as well as other characteristics of the subject, such as baseline clinical data. The treatment can be administered when the response value is beyond a threshold.
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