Patent · US Active

Combination of estrogens plus antiprogestins with significant partial agonistic effect as an effective treatment of menopausal symptoms and for prevention of the occurrence of breast cancer

US9850273B2 · kind B2 · utility

0Cited by

3References

13Claims

0Family size

Assignee

Evestra, Inc. · US

Inventors

Klaus Nickisch · Berlin, DE
Bindu Santhamma · San Antonio, US
Hareesh Nair · San Antonio, US
Walter Elger · Berlin, DE

Key dates

Filing date	Dec 3, 2015
Grant date	Dec 26, 2017
Priority date	—
Expiry date	Dec 3, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J71/001
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described herein are compositions and methods for hormone replacement therapy that address the shortcomings of the existing methods. Described herein are pharmaceutically effective partial agonistic antiprogestins. The combined application of estrogens (such as estradiol, estriol and conjugated estrogens) and the disclosed partial agonistic antiprogestins can be used in hormone replacement therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.