Enzymatic synthesis of L-nucleic acids

US9850471B2 · kind B2 · utility

Assignee

• NOXXON Pharma AG · DE

Inventors

• Andreas Pech · Bodenwerder, DE
• Ralf David · Leipzig, DE
• Florian Jarosch · Berlin, DE
• Michael Jahnz · Berlin, DE
• Sven Klussmann · Berlin, DE

Key dates

• Filing date: May 16, 2013
• Grant date: Dec 26, 2017
• Expiry date: May 16, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y207/07
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a method of reacting one or more L-nucleotides with a first L-nucleic acid in the presence of a D-enzyme that adds the one or more L-nucleotides to the 3′ end of the first L-nucleic acid.