Determination of the normalized degree of DNA methylation
US9850528B2 · kind B2 · utility
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1References
15Claims
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Inventor
Key dates
| Filing date | Jan 21, 2010 |
| Grant date | Dec 26, 2017 |
| Priority date | — |
| Expiry date | Jan 21, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/154
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides oligonucleotides and processes for determining the normalized methylation level of DNA, and for determining the relative methylation level of DNA between at least two samples. The invention makes use of the random distribution of transposons in the genome. The disclosed oligonucleotides and processes are of importance, in particular, for clinical diagnostics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.