Biomarkers associated with BRM inhibition
US9850543B2 · kind B2 · utility
1Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 12, 2014 |
| Grant date | Dec 26, 2017 |
| Priority date | — |
| Expiry date | Mar 12, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/914
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods of detecting cancer biomarkers, such as one or more SWI/SNF complex mutations, in order to determine a cancer subject's amenability to therapeutic treatment with a BRM inhibitor. Kits, methods of screening for candidate BRM inhibitors, and associated methods of treatment are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.